Phentrmine
Pronunciation:
FEN-ter-meen
Brand
Names: Adipex-P, Fastin,
Ionamin, Obenix,
Obephen, Oby-Cap, Oby-Trim, Panshape
M, Phentercot, Phentride, Pro-Fast
HS, Pro-Fast SA, Pro-Fast SR,
Teramine, Zantryl
Risk
Factor:CM
Phentrmine
pictures:
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Ionamin 30 mg
Manufactured by
Medeva Pharmaceuticals, Ionamin is
the only resin matrix capsule
available in the market. |
Adipex-P 37.5 mg
Produced by Gate
Pharmaceuticals, Adipex-P is the
leading brandname of
Phentrmine. |
Generic Capsules 15 mg
(Eon)
Produced by Eon
Laboratories, the leading
manufacturer of generic
Phentrmine. |
Generic Capsules 30 mg
(Eon)
The most common
dosage of generic Phentrmine Sold in
the US, produced by Eon
Laboratories. |
Generic Tablets
37.5 mg (Purepac) Produced by
Purepac, another leading
manufacturer of generic
Phentrmine. |
What is
Phentrmine?
Oral Phentrmine
Hydrochloride (HCL) is sold for
weight loss. It is in the
Sympathomimetic
family of
appetite suppressants
(used for the short-term management
of exogenous obesity.) When used in
conjunction with diet, exercise, and
behavior therapy, Phentrmine may
help you to lose weight while you
are learning new ways to
eat and to exercise.
History of
Phentrmine
Phentrmine is the
most commonly prescribed prescription
appetite suppressant, accounting
for 50% of the
prescriptions. Part of this reason is
because it's significantly cheaper
than the other major
FDA-approved diet drugs, Meridia and
Xenical.
Phentrmine first received approval
from the Food and Drug Administration
(FDA) in 1959 as an appetite
suppressant for the short-term
treatment of obesity.
Phentrmine resin became available
in the United States in 1959 and
Phentrmine Hydrochloride in the
early 1970s.
In the US, Phentrmine is currently
sold under the brand names Ionamin®
(Medeva Pharmaceuticals) and
Adipex-P® (Gate Pharmaceuticals). It
is also available as a generic
medication, known as 'Phentrmine'.
Previously, it was sold under the
name Fastin® (formerly produced by
King Pharmaceuticals for SmithKline
Beecham). In December 1998,
SK-Beecham withdrew Fastin from the
market.
As Phentrmine is an older drug, no
new efficacy trials have been
conducted. The one notable exception,
are several trials on the combination
of Phentrmine and Fenfluramine in
the early and mid 1990s.
How
does Phentrmine work?
Phentrmine works by
stimulating the hypothalamus gland
and affecting certain
neurotransmitters to
decrease appetite. The hypothalamus
is the region of the brain that
controls the autonomic nervous
system, regulating sleep cycles, body
temperature, appetite, etc.
Proper Use of
Phentrmine
Phentrmine should be
taken on an empty stomach, once
daily, prior to breakfast. If in
tablet form, the
tablet may be broken or cut in half.
Do NOT break, crush, or chew tablets.
As Phentrmine may disrupt normal
sleep patterns, avoid taking a dose
late in the day. If taking more
than one dose a day, take the last
dose approx. 4-6 hours prior to going
to bed.
The following information is
specific only to the average doses of
Phentrmine. The recommended dose of
Phentrmine may be different for
different patients. If your dose is
different, do NOT change it unless
your doctor tells you to do so.
Adults under Age 60
Oral dosage form (Capsules) - 15 to
37.5 mg once/day before breakfast or
1-2 hours after breakfast.
Oral dosage form (Tablets) - 15 to
37.5 mg once/day before breakfast or
1-2 hours after breakfast.
Instead of taking it once a day, your
doctor may tell you to take 15 to
37.5 mg in divided doses
one-half hour before meals.
Oral resin dosage form (Capsules) -
15 to 30 mg once/day before breakfast.
Adults Age 60 and Over
A reduced dosage may be necessary.
Consult your physician.
Infants and Children
Phentrmine is NOT recommended for
children under age 16.
Maximum Dosage
Recommendations
Take Phentrmine ONLY
as directed by your doctor.
Do NOT take more of it
Do NOT take it more often, and
Do NOT take it for a longer time
than your doctor ordered.
If too much Phentrmine is taken,
it may cause unwanted effects or
become habit-forming.
Please speak with your doctor if
you think that Phentrmine is not
working properly after you have taken
it for a few weeks. DO NOT increase
the dose.
Storage
Keep this and all
medications out of children's reach.
Store away from heat and direct light.
Do NOT store in the bathroom, near
the kitchen sink, or in other damp
places. Heat or moisture may cause
the medicine to break down.
Do NOT keep outdated medicine past
the expiration date. Discarded
medicine should be kept out of
children's reach.
Ending Phentrmine
Treatment
After you stop taking
Phentrmine, your body may need time
to adjust. The length of time
this takes
depends on the amount of medicine you
were using and how long you used it.
During this time, speak to
your doctor if you notice any side
effects (as noted above in Physical
or Mental Dependence on
Phentrmine).
If you have been taking Phentrmine
in large doses or for a long period
of time, do NOT stop taking it
without first consulting your doctor.
S/he may want you to gradually reduce
the amount you are taking
before stopping completely. This will
help prevent withdrawal side effects.
Important Notes
concerning Phentrmine and Weight
Loss
Phentrmine should
NOT be used as a substitute for
proper diet or exercise. For maximum
effects, it must
be used in conjunction with a
reduced-calorie diet and/or exercise.
Any modifications in your diet,
activity level, and behavior must be
developed and continued long-term
in order to continue losing weight
and prevent the lost weight from
returning.
As Phentrmine is similar
chemically to amphetamines, taking
Phentrmine may cause a positive
result in
urine screening tests for amphetamines.
Do NOT share your Phentrmine
prescription with others.
Consult your doctor or pharmacist
for further information on
Phentrmine.
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